"We look for the resurrection of the dead, and the life of the world to come. Amen"
The Council of Constantinople, Nicene Creed (381).
While consensus of redundantly- and manuallyh-traced neurites and annotated synapses is one appraoch, it relies on model-based assumptions.I'm not sure what "model-based assumptions" here means but I'm guessing he's saying that a bunch of human annotators look at a reconstruction and agree, "this looks right." Some other (better) options are:
Someone at dinner used the phrase "when the worms get me" and I immediately reached under my collar to make sure I was wearing my magical anti-death amulet. So glad I'm signed up for Cryonics.
Here we describe a preparation, BROPA (brain-wide reduced-osmium staining with pyrogallol-mediated amplification), that results in the preservation and staining of ultrastructural details throughout the brain at a resolution necessary for tracing neuronal processes and identifying synaptic contacts between them. Using serial block-face electron microscopy (SBEM), we tested human annotator ability to follow neural ‘wires’ reliably and over long distances as well as the ability to detect synaptic contacts. Our results suggest that the BROPA method can produce a preparation suitable for the reconstruction of neural circuits spanning an entire mouse brain
|Comparison OF BROPA to the similar but older ROTO|
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Human reasoning is based on an understanding derived from a combination of personal experience and collective knowledge derived over generations, explains MIRI researcher Nate Soares, who trained in computer science in college. For example, you don’t have to tell managers not to risk their employees’ lives or strip mine the planet to make more paper clips. But AI paper-clip makers are vulnerable to making such mistakes because they do not share our wealth of knowledge. Even if they did, there’s no guarantee that human-engineered intelligent systems would process that knowledge the same way we would.I'd always thought that no one would be stupid enough to attach a superintelligent computer to actuators that could seriously affect the world but I've come to see that that is naive. The moment an AI is shown to be successful in a small field, it will almost instantly be given greater and greater responsibilities so that its owners can reap maximum rewards.